Hemodynamics of C-Pulse
Dimitrios Georgakopolous, PhD
This presentation highlights the mechanism of action of the C-Pulse, a device used in the treatment of moderate to advanced heart failure. The C-Pulse consists of a cuff which is placed externally on the ascending aorta, and operated on the principle of counterpulsation. Data are presented from preclinical and clinical studies demonstrating effects on arterial properties including afterload reduction, coronary and renal blood flow. Data are also presented highlighting mechanism of C-pulse involving modulation of the autonomic nervous system.
Indication: The Aquadex System is indicated for temporary (up to 8 hours) ultrafiltration treatment of patients with fluid overload who have failed diuretic therapy; and extended (longer than 8 hours) ultrafiltration treatment of patients with fluid overload who have failed diuretic therapy and require hospitalization. All treatments must be administered by a healthcare provider, under physician prescription, both of whom having received training in extracorporeal therapies.